CBG: discover how Cannabigerol works in the body
The difference between CBD and CBG is not limited to the gram that differs. In fact, Cannabigerol (CBG) interacts completely differently with our body’s endocannabinoid system (ECS) than Cannabidiol (CBD) – from the same industrial hemp plant – but how exactly is this and what effects can you expect from CBG oil?
Find out what scientific research has found about it so far:
What is Cannabigerol (CBG) from CBG oil?
Like Cannabidiol (CBD), Cannabigerol (CBG) is a non-psychoactive cannabinoid from industrial hemp.
Very important, we might add. Whereas CBG is the precursor of two of the most prevalent cannabinoids in industrial and medicinal cannabis plants. This means that both CBD and tetrahydrocannabinol (THC) were at one time CBG molecules, before eventually being converted to another cannabinoid in the plant.
As we explained in our previous article: “What is CBG Oil? Discover the difference between CBD and CBG “
This also means that Cannabigerol is generally present in higher concentrations in early harvested cannabis plants.
After all, most of it has already been converted to CBD or THC in plants that are ready to be harvested. This is why you will find only small amounts of the substance in the majority of available CBD products, in support of the synergistic effect. However, CBG oil can have a positive impact on our well-being, just like CBD oil. Although Cannabigerol does it differently than Cannabidiol from CBD oil…
The effect of CBG on the ECS
CBD is known to inhibit the breakdown of our “happiness molecules” such as anandamide and 2-AG. These cannabinoids are produced by the body and are signalling substances (neurotransmitters) that belong to our endocannabinoid system (ECS). Proven by a growing body of research, this is the reason behind the effectiveness of CBD on the body. As CBD can bring more balance to your hormonal state, giving your body a chance to restore itself better. It is also the main reason behind the rejuvenating effects of CBD, for example.
Although CBG seems to have another interaction with the endocannabinoid system.
Relaxing effects of CBG
While CBD focuses on delaying the breakdown of 2-AG and anandamine, CBG oil on the other hand inhibits the breakdown of GABA. This is an amino acid that we produce naturally and is mainly responsible for neutralizing certain stimuli in the brain. Consequently, GABA helps regulate motor function, vision and a range of emotional responses, such as stress and anxiety.
This relaxation caused by CBG and GABA is mostly physical, at first. Considering that it helps to reduce muscle tension and generally helps to reduce extreme nerve activity, it is likely to lead to a feeling of rest and relaxation in the body.
Although according to research, CBG is also able to help regulate the stress response to combat or flight stress, which the human body naturally activates in stressful situations. However, in some cases the body activates this stress unnecessarily – potentially causing chronic stress and anxiety disorders. Fortunately, Cannabigerol is able to upregulate the α2-adrenergic receptor, reducing the release of the neurotransmitter that causes norepinephrine or noradrenaline causing anxiety. In other words, CBG oil could calm the body and mind by its unique effect on these ECS receptors.
The effects of CBG oil on the body
Besides, there are some other properties of Cannabigerol that are being researched by science. For example, there are studies that claim that this cannabinoid may have painkilling properties. This may have to do with the muscular and relaxant neural effects of CBG’s interaction with the receptors explained above. Although what may also play a role is the anti-inflammatory properties of the substance. Because other research shows that CBG has powerful anti-inflammatory properties, it could potentially prevent oxidative stress. This is also demonstrated in another study, which focused mainly on the potential anti-inflammatory properties of CBG in the digestive system. It shows promising results in the fight against Crohn’s disease.
In addition, CBG also appears to have neuroprotective properties. For example, it offers promising potential for delaying the onset and development of Huntington’s disease. Although we should note that these are preliminary results based on mice. Therefore, there is absolutely no guarantee that CBG oil can help with Huntington’s disease. But it certainly won’t hurt!
Other possible effects of CBG
And if you thought the potential positive effects of CBG stopped there, you’re in for a treat. Because Cannabigerol can also be very useful to the body, instead of just to it. For example, research shows that CBG may help slow down excessive cell proliferation in the skin. This means that Cannabigerol could be useful in the treatment of psoriasis and eczema and could help to slow down skin ageing.
In addition, we have seen studies claiming that CBG can help treat certain types of cancer. The use of CBG appeared to be particularly useful in slowing the development of skin cancer and colon cancer in various laboratory experiments. This has not yet been tested in humans and there is absolutely no guarantee that it will cure any type of cancer.
Finally, we found the antibacterial properties of CBG to be remarkable. Because according to scientific research, Cannabigerol works extremely well against bad bacteria. So well, in fact, that it could even help treat “untreatable” MRSA bacteria, if the research paper is to be believed.
Like most research on the active constituents of cannabis, the aforementioned studies are mainly performed in vitro in petri dishes, or experiments using live rats and mice at best. The above information cannot be used as medical advice and is not intended to replace medical advice. There is a need for more human research – so that this substance from industrial hemp can get the recognition it deserves.