Many different types of CBD products are available on the market, all with different effects.
But little is known about the exact content and function of the various products.
CO2 extract (CBD paste)
A CO2 extract is, as the name suggests, a cannabis concentrate whose active ingredients have been extracted from the plant material with the help of CO2. CO2 not only ensures that the CBD is pulled from the plant material, but also the fats, sugars, other cannabinoids and terpenes
CO2 is often used in the food industry to produce extracts because it extracts everything from the plant material.
In a CBD extract with CO2 1/3 of the content is wax, which gives it a paste-like structure.
Because it is viscous, usually a CO2 extract is offered in syringes.
The bioavailability of a CO2 extract is just like a typical CBD oil about 6-12%.
This means that only 6% to 12% is absorbed by the body. The amount of CBD present in a CO2 extract depends on the type of cannabis used, the time of harvest, the climate and the knowledge of the extractor.
CBD oil based extract
Most types of CBD oil on the market are produced from a CO2 extract that has been diluted with an oil such as olive oil, hemp seed oil or coconut oil. Hemp seed oil sometimes cannot be preserved for such a long time and coconut oil has the disadvantage of solidifying, causing lumps to form. Coconut oil must be heated before it can be consumed.
CBD oil is usually sold in a dropper bottle and is therefore usually an extract diluted with an oil such as olive oil, hemp seed oil or coconut oil.
Bioavailability is 6-12%, as is hemp extract (CBD paste).
Because a CBD oil is a dilution of an extract, it always contains less CBD than a pure extract.
CBD oil based on crystals
There are also more and more types of CBD oil on the market that are made on the basis of CBD crystals. These crystals are of natural or synthetic origin, where the difference is indistinguishable. The natural crystals are isolated from the hemp and purified in such a way that a solid crystalline substance is formed.
There is nothing wrong with natural CBD crystals, they can be used safely.
Synthetic CBD is made by reacting different chemicals to simulate the biological composition of the plant. Natural CBD and synthetic CBD are exactly the same with exactly the same effect. However, other compounds may arise during the production process of synthetic CBD that could potentially be harmful and even cause unpleasant side effects. There will also always be residues from the chemical reaction in the synthetic CBD crystals. The biggest disadvantage of a crystal-based CBD oil is that the difference between natural and synthetic CBD crystals is very difficult to distinguish. Synthetic crystals are almost always sold as natural CBD crystals and oil manufacturers cannot tell the difference without the intervention of a specialist laboratory. Another disadvantage of a CBD crystal-based oil is that it only contains CBD and therefore lacks many other cannabinoids and terpenes, so the medicinal effect is always less than a CBD oil that contains other cannabinoids and terpenes.
CBD oil at Nano level
A relatively new form of CBD oil is CBD oil at the nano level.
CBD crystals or hemp extract are brought to the nano level through ultrasonic frequencies. According to the sellers of this oil, the bioavailability is many times higher and this oil, according to the sellers, is much better absorbed by the body.
Function of Nano CBD oil
Nano CBD is nothing more than CBD with a smaller particle size. CBD crystals are used to grow nano CBD and also hemp extracts. The molecule is made smaller with the help of ultrasonic frequencies, but the lipophilic properties of CBD remain the same. Although Nano CBD is smaller and therefore easier to absorb by the body, Nano CBD still needs to be bound by the body into a lipoprotein. As a result, much of Nano CBD is broken down by enzymes in the liver.
Nano CBD is not allowed and there are also great risks behind this technique.
For example, you do NOT want to take cannabis extract at the nano level because the heavy metals that may be present in the extract have also been converted to nano particles, which you naturally prefer not to have in your body. Nano CBD is better absorbed by the body than regular CBD oil, but it still has limitations.
Like regular CBD oil and crystal-based oil, with CBD nano oil you also lose all the other therapeutic substances, such as other cannabinoids and terpenes.
In addition, there are government restrictions that currently prevent the production and sales of Nano CBD. Food authorities in the EU have stated that Nano CBD is NOVELL and is banned and cannot be sold on the market. The authorities have also indicated that they will maintain this ban on all Nano supplements in general and therefore also Nano CBD oil.
CBD oil based on lecithin / liposomes
An increasing number of CBD oils are now offered on the market based on lecithin.
Lecithin is a so-called emulsifying agent and can therefore bind fats with water. Lecithin is very common in eggs, soy and sunflower seeds and is used, for example, to make mayonnaise. It has been reported that CBD formulations made with lecithin are more easily absorbed by the body as a result of lecithin binding. Comparisons are often made with so-called liposomal types of vitamin C, where lecithin is also used to ensure that vitamin C is absorbed more efficiently by the body. Lecithin ensures that fats can bind to the body, so that they can be broken down efficiently. At the cellular level, lecithin is essential for healthy cell function. Lecithin is certainly a healthy dietary supplement, but will it really help the absorption of CBD in the body as well?
Lecithin / liposome effects with CBD
Lecithin can ensure that fats are bound to water, which we refer to as emulsion. Lecithin can therefore bind fatty substances such as CBD and mix them with water. However, the binding of CBD to lecithin is a very difficult process and the water solubility at room temperature is very low. The binding strength of lecithin is stronger than that of the body’s own lipoprotein, which means that CBD bound to lecithin will be absorbed even less efficiently than a standard olive oil-based CBD oil.
In fact, as lecithin ensures the binding of fats and fatty substances, lecithin is ideal for use as a natural cholesterol reducer and as a slimming agent. As cannabinoids are also stored in tissue, lecithin can ensure that CBD is removed from the body at a faster rate. Lecithin binds CBD in the body and ensures that it is expelled from the body faster through the urinary tract. Therefore, you could effectively use lecithin to remove, for example, THC from the system, but not achieve better absorption of CBD or THC, as lecithin’s strong fat-binding properties mean that it has a counterproductive effect on the absorption of lipophilic substances such as CBD and THC. On the other hand, lecithin can end up in water-soluble substances such as vitamin C that are more efficiently absorbed by the body, leading to a higher blood level which is not possible without lecithin binding, with the exception of intravenous administration. This is referred to as a liposomal solution of vitamin C. This therefore works with water-soluble vitamins, but not with lipophilic (fat-soluble) substances such as THC and CBD!
The CBD based BioACTIVE+ (CBDactive+)
A BioACTIVE+ based CBD oil will be absorbed more efficiently than traditional CBD oil, as BioACTIVE+ contains a complex that acts as a transporter (lipoprotein) in the bloodstream, meaning that the CBD will not have to first bind to a lipoprotein from the body before it can enter the bloodstream.
CBDActive + Water soluble
How does CBDactive+ work?
CBDactive+ was developed to increase the bioavailability of CBD and make CBD water soluble, ensuring that CBDactive+ is not only absorbed more efficiently, but will have more application potential than traditional oil-based CBD supplements. CBD is a lipid component and must be metabolized by the body after ingestion, where the body must bind the CBD to a lipoprotein (transporter) in order for the CBD to pass into the bloodstream. The body makes CBD itself water-soluble – as a result of binding to the bodies own lipoproteins. As the body makes CBD itself water soluble, CBD can be absorbed into the blood, which, of course, consists of> 90% water. As the body has to carry out the same complex metabolism in order to make CBD water soluble, almost 95% of CBD is broken down by the liver during metabolism and only about 5% will eventually reach the bloodstream. The body would be able to make the 5% CBD that would eventually reach the bloodstream water-soluble by binding the CBD (lipid) to a lipoprotein.
CBDactive+ contains an advanced complex, which binds to CBD and acts as a lipoprotein (carrier) in the bloodstream. Therefore, bound CBD is directly water soluble. As the CBD is already bound as a result of the BioACTIVE+ Formula in the supplement, the body will not need to do complex metabolism to get the CBD into the bloodstream. This means that the body will actually absorb 99% of the bound CBD, based on BioACTIVE+ Formula.
Another advantage of a CBD product based on the BioACTIVE+ formula is that all the terpenes naturally occurring in cannabis will result in a complete environment and will have some effect on the Cytochrome P450 enzyme so that the active ingredients are broken down more slowly.